Implementation Science

How do we translate research findings into programs and policies that work?

Too often, there are gaps between research and practice -- research is conducted in controlled settings without engaging with dynamics of real-world implementation, and practitioners lack access to research tools and findings that are useful in their work. At HART,  our projects try to bridge these gaps, conducting research within community settings, designing evaluations that operationalize intervention components, and developing frameworks for using research findings in day-to-day practice. Our implementation science projects are conducted in collaboration with community partners at every step of the research process -- from conceptualization of research questions to development of measures and data collection protocols to analysis and dissemination.   


Project IMPrOVE: Understanding Implementation of HIV Prevention Navigation in STD Clinics (R01MH106380-02S1; Golub, PI)

Project IMPrOVE is a partnership between HART and the New York City Department of Health and Mental Hygiene (DOHMH) to evaluate a new model of STD clinic-based PrEP navigation and implementation. We want to understand how this new intervention works -- Which patients does it help most and why? Which components of the program are most or least effective? How can program elements be modified to best serve highest priority patients? We are collecting data from patients who accept and refuse navigation services and following them over time. We are also using the Proctor Implementation Science Framework (Proctor et al., 2013) to operationalize program components, monitor fidelity, and better understand optimal outcomes.

READY: Preparing for Implementation of Sustained Release Antivirals for HIV Prevention (R01MH105268 ; Golub, PI)

Long-acting injectable (LAI) formulations of anti-retroviral medications are currently being studied for use in HIV prevention. Such LAI products have many advantages, but may also face challenges -- How acceptable will these product be? Which patients will be most (and least) interested in them? How should patient education materials be developed and what guidelines should providers be given to assist them in delivery of these new products? This project takes a multi-modal approach to identifying relevant healthcare system delivery factors, provider dynamics, and patient preferences that might inform optimal delivery of long-acting ARV formulations for HIV prevention (LAI PrEP), and develops specific recommendations for provider education, clinical guidance, and strategies for optimizing delivery of LAI PrEP to highest priority populations. We are partnering with the Health Outreach to Teen (HOTT) program at Callen-Lorde Community Health Center and the Hetrick Martin Institute (HMI) to answer these research questions. 


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Select Publications

Meyers, K. and Golub, S.A. (2015) Planning ahead for implementation of long-acting HIV prevention: Challenges and opportunities. Current Opinion in HIV/AIDS, 10(4):290-295.

Golub, S.A., Operario, D., & Gorbach, P.M. (2010).  Pre-exposure prophylaxis state of the science: Empirical analogies for research and implementation.  Current HIV/AIDS Reports, 7(4):201-209.